Diagnosing the Future: Proteins, Biosensors and Fundamental Science with Prof. Eleonora Macchia
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Can a single drop of blood tell you whether you'll develop pancreatic cancer — before any symptoms appear? Prof. Eleonora Macchia is working to make that a reality. This week on SciLux, we dig into biosensors, the science of proteins, and the surprising path from organic transistors to clinical trials.
What you'll learn:
Why the proteome is medicine's great unknown
How current tests (ELISA, lateral flow) fail at ultra-low concentrations, and what SiMoT technology does differently
What it actually means to detect a single molecule in a patient's blood sample
Why AI in diagnostics is only as good as the physicist standing behind the data
How chemometrics – AI's "old-fashioned cousin" – underpins the whole approach
Key Themes:
Frontier research and ERC funding advocacy
Single-molecule biosensing and the SiMoT technology
Preventive medicine vs. reactive diagnosis
AI, chemometrics, and data quality
Circular health and multidisciplinary science
Gender balance in research careers
Guest: Prof. Eleonora Macchia, University of Bari & Åbo Akademi University
USEFUL LINKS
More about Prof. Eleonora Macchia: https://scholar.google.com/citations?user=tj6pKhAAAAAJ&hl=en
ERC Ambassadors: https://erc.europa.eu/news-events/news/network-ambassadors-erc-expands
More about SiMoT: https://theanalyticalscientist.com/issues/2024/articles/apr/the-single-molecule-sensor
University of Bari: https://www.uniba.it/en
Åbo Akademi University: https://www.abo.fi/en/
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